April 3, 2025 10:30 – 12:00 pm – Wu and Chen Auditorium – Levine Hall
Kyocera Chair Professor of Materials Science and Engineering, University of Washington
“Multifunctional Nanoparticles for Targeted Cancer Imaging and Treatment“
Abstract: One of our key research areas focuses on developing innovative nanoplatforms for cancer diagnosis, treatment, and therapy-response monitoring. We aim to understand material-biosystem interactions and design nanoparticles capable of delivering effective therapeutic payloads. This presentation will discuss strategies for synthesizing and engineering nanoparticles to ensure stability, extended blood circulation, and controlled drug release while overcoming biological barriers. I will also highlight the applications of our nanoparticle formulations in targeted delivery of DNAs, siRNAs, and mRNAs, integrated with chemotherapy, radiation, and immunotherapy. Our scalable and safe nanoparticles demonstrate effectiveness in overcoming therapy resistance, metastasis, and tumor recurrence in various murine models.